UHF Methodology and Hardware - H. H. Quick

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UHF Methodology and Hardware

H. H. Quick
UHF Methods and Hardware DevelopmentRadiofrequency (RF) coils for 7T Brain & Body MRIClinical application of 7T UHF MRIMRI Safety and Implants
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The PI group "High-Field and Hybrid MR Imaging" directed by Professor Harald H. Quick develops and evaluates new methods and hardware to broaden the spectrum of 7-Tesla ultrahigh-field magnetic resonance imaging (7T UHF MRI).

Specifically, new multi-channel radiofrequency (RF) transmit/receive coils for 7T brain & body MRI are simulated, designed, and evaluated. The ultimate aim of these efforts is to assess the high signal-to-noise-ratio (SNR) inherent to UHF-MRI and to apply this to high-resolution imaging in various brain and body UHF MRI applications.

The research groups of Prof. Harald H. Quick and Prof. Mark Ladd (DKFZ, Heidelberg) work in close cooperation to achieve this aim in 7-Tesla whole-body MRI. The ELH PI groups of Harald Quick and Tom Scheenen have joined forces to develop new methods and RF coils to enable high spatial resolution 7T prostate and pelvis imaging as clinical application of UHF MRI.

Further active collaborations exist with various clinical users of 7T UHF MRI from the University Hospital Essen. Field strength comparison studies serve to evaluate the clinical advantages and disadvantages of 7T UHF MRI when compared to 1.5T and 3T MRI. A further research focus of the PI group Quick is on all MRI related safety aspects and when imaging patients with passive and active implants.

Current projects
  • EU MITI: Non-ionizing Metabolic Imaging for predicting the effect of and guiding Therapeutic Interventions (MITI) 2022 - 2024, EU HORIZON-EIC-2021, Project Number 101058229
  • DFG: SFB 1280 "Extinction Learning" 2021-2025, Project Number 316803389, PI of the projects A05 "The contribution of the cerebellum to extinction: intrinsic mechanisms and cerebello-cerebral interactions" and F02 "Focus Group Neuroimaging and Genetics"
  • Medical Faculty, UDE: IFORES: Impact and long-term compatibility of Perfluorocarbon-based albumin capsules on regenerative capacity of small animals model, after high blood loss 2019 - 2022
Selected Publications
  • Voelker MN, O Kraff, S Goerke, et al., The traveling heads 2.0: Multicenter reproducibility of quantitative imaging methods at 7 Tesla., Neuroimage (2021)
  • Orzada S, K Solbach, M Gratz, et al., A 32-channel parallel transmit system add-on for 7T MRI., PLoS One (2019)
  • Ernst TM, AE Brol, M Gratz, et al., The cerebellum is involved in processing of predictions and prediction errors in a fear conditioning paradigm., Elife (2019)
  • Grüneboom A, I Hawwari, D Weidner, et al., A network of trans-cortical capillaries as mainstay for blood circulation in long bones., Nat Metab (2019)
  • Pfaffenrot V, S Brunheim, SHG Rietsch, et al., An 8/15-channel Tx/Rx head neck RF coil combination with region-specific B1 + shimming for whole-brain MRI focused on the cerebellum at 7T., Magn Reson Med (2018)
  • Rietsch SHG, S Orzada, S Maderwald, et al., 7T ultra-high field body MR imaging with an 8-channel transmit/32-channel receive radiofrequency coil array., Med Phys (2018)
  • Brunheim S, M Gratz, S Johst, et al., Fast and accurate multi-channel B1+ mapping based on the TIAMO technique for 7T UHF body MRI., Magn Reson Med (2018)
  • Kraff O, HH Quick, Radiofrequency Coils for 7 Tesla MRI., Top Magn Reson Imaging (2019)
  • Kraff O, HH Quick, 7T: Physics, safety, and potential clinical applications., J Magn Reson Imaging (2017)
  • Quick HH, Integrated PET/MR., J Magn Reson Imaging (2014)
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