For all those who were unable to attend the Erwin L. Hahn Lecture & Workshop 2021, whether virtually or directly on site, a video recording of the key note by Prof Dr Oliver Speck from Otto von Guericke University Magdeburg is now available on the event site.
In his one-hour guest lecture, Professor Speck spoke about "High resolution structural and vascular MR imaging at 7T" and provided fascinating insights into his research work.
Hosting a conference as a hybrid event – as for many others, it was the first time for the Erwin L. Hahn Institute for MRI. For the 14th edition of the Erwin L. Hahn Lecture & Workshop on November 3rd, the ELH had decided to host the meeting both as a physical event - on a smaller scale than usual and with strict COVID-19 regulations - and on a digital platform. It was anybody’s guess how well the offer would be received, but the ELH is fully satisfied with the result.
While about half of the usual number of participants did not want to miss the opportunity to finally meet old friends and colleagues "in the flesh" and network in the cosy and inviting atmosphere of the Oktogon at the Zollverein World Heritage Site, there were over 200 individual accesses to the live stream of the Erwin L. Hahn Lecture & Workshop during the course of the day. This means that the event was able to reach more people than ever before - a great result.
Under the overarching theme "New perspectives on vascular anatomy and function", the invited guests and participants discussed new research results in the field of vascular diseases and how ultra-high field MRI can be useful in the research and diagnostics of these diseases.
The ELH was also able to win Prof. Dr. Oliver Speck from Otto von Guericke University Magdeburg for the keynote speech, whose presentation provided fascinating insights into the topic of "High resolution structural and vascular MR imaging at 7T".
This year's Erwin L. Hahn Young Scientists Award was presented to Dr. Thomas M. Ernst, who successfully defended his dissertation entitled "On the importance of the cerebellum for emotional control using the example of acquisition and extinction of conditioned fear responses" in September and was awarded "summa cum laude". In his thesis, Dr. Ernst focuses on the role of the human cerebellum in fear conditioning and its importance in anxiety disorders.
The ELH would like to thank all participants, speakers and Prof. Dr. Speck for an all-round successful event.
Erwin L. Hahn Lecture & Workshop: https://hahn-institute.de/de/hahn-lecture
How can ultra-high field magnetic resonance imaging (UHF MRI) be used in cancer diagnostics, and what possibilities does it entail? For many years now, Prof. Dr. Tom W. J. Scheenen from the Netherlands has been conducting research in this field both in Nijmegen and with a PI group at the ELH.
As of October 2021, Prof. Scheenen has taken up his full professorship in the Department of Biomedical Magnetic Resonance at Radboudumc in Nijmegen. Working as a biophysicist in a clinical environment gives Prof. Scheenen the unique opportunity to integrate his knowledge of the methodology of UHF MRI directly into clinical practice, especially oncology.
We congratulate him on his professorship!
This September, Dr. Thomas M. Ernst successfully defended his PhD thesis titled "On the importance of the cerebellum for emotional control using the example of acquisition and extinction of conditioned fear responses".
In his dissertation, which was assessed with "summa cum laude", Dr. Ernst addressed the question of the extent to which the cerebellum is involved in the conditioning of fear responses. Dr. Ernst ist part of Prof. Dr. Timmann-Braun’s research group.
After a long and successful career in the research and application of magnetic resonance spectroscopy (MRS) and magnetic resonance imaging (MRI), Prof. Dr. Arend Heerschap of the Radboudumc is retiring today. In his work, Prof. Dr. Heerschap was particularly dedicated to the application of magnetic resonance in oncology and the study of energy metabolism.
The importance of his work was reflected not only in the numerous funded projects, but also in the positions Prof. Dr. Heerschap took on: In addition to his research activities, he was also an executive member of the ESMRMB, the elected chair of the oncology section of the ISMRM and served as a reviewer for various journals. In addition, he supervised over 15 PhD students during his career.
In 2014, Prof. Dr. Heerschap was a key speaker at the Erwin L. Hahn Workshop&Lecture.
The Erwin L. Hahn Institute wishes Prof. Dr. Arend Heerschap a long and happy retirement.
What exactly is the cerebellum’s purpose, and why has it remained unexplored for so long? What is the cerebellum, where is it located and what are its functions exactly? Why is the term "ataxia" rather fuzzy, and why is Otto's legendary "cerebellum to cerebrum" sketch surprisingly accurate?
Prof. Dr. Dagmar Timmann-Braun answers these and other questions in the eighth episode of the Ruhr University Bochum podcast "Kannste vergessen", which is dedicated to the Collaborative Research Centre 1280. Together with Prof. Dr. Melanie Mark, Professor of Behavioural Neurobiology, Prof. Dr. Timmann-Braun was interviewed by moderator Rainer Holl's in a relaxed conversation. Prof. Dr. Timmann-Braun is one of the project leaders in the CRC 1280.
The episode "Cerebellum to Cerebrum“ is available here: [LINK]
The Erwin L. Hahn Institute has again received reinforcement - cognitive neuroscientist Prof. Dr. Nikolai Axmacher from the Ruhr University Bochum has joined the ELH with a research group.
With the help of his scientists, Prof. Axmacher is investigating the neuronal mechanisms of memory and spatial navigation in healthy people as well as neurocognitive changes in post-traumatic stress disorder and early Alzheimer's disease.
The research group hopes to decipher what we remember as well as how we remember it. The unique spatial resolution of fMRI measurements at 7T at the ELH allows these processes to be studied at an even more mechanistic level.
The hippocampus serves as an important central structure for cognitive functions such as memory and spatial navigation. However, until now it hasn’t really been possible to investigate how exactly the processes take place in this part of our brain, as they happen in individual cell layers that were previously almost impossible to visualise with conventional imaging.
Recently though, the spatial resolution of human ultra-high field imaging has been improved to such an extent that the activity of different cell layers can be examined separately. In the MERCUR-funded project "Laminar ultrahigh-field imaging in the human hippocampus" by ELH-Associated PI Prof. Dr. Nikolai Axmacher and ELH Director David G. Norris, measurement methods to also advance laminar - i.e. cell layer-specific - imaging of the hippocampus are to be developed. The goal is to map the neuronal processes in the human hippocampus and their importance for memory and navigation.
The project lays the foundation for a larger research DFG-funded programme on the cognitive function of hippocampal cell layers and their interaction with neocortical and subcortical regions.
How we remember and how this influences how we come to expect things - the joined NeuroMind research consortium of the UDE and the Ruhr-Universität Bochum (RUB) is trying to answer exactly these questions. The Mercator Research Center Ruhr (MERCUR) has decided to fund the exciting project for five years from January 2022 with around two million euros. The Erwin L. Hahn Institute will play a central role in the project.
Three PIs of the Erwin L. Hahn Institute and their research groups are directly involved: In addition to the RUB biopsychologist Prof. Dr. Onur Güntürkün (spokesperson), Prof. Dr. Ulrike Bingel as well as ELH Director Prof. Dr. Matthias Brand and their research groups play a major role. A total of 56 researchers are participating in the interdisciplinary project, and international partners are also involved.
Of the six projects approved by MERCUR, an additional one is based at the ELH: "Laminar ultra-high field imaging in the human hippocampus" is being conducted under the leadership of ELH Director David G. Norris.
On June 11, 2021, the Faculty of Medicine at the University of Duisburg-Essen hosted a digital PhD graduation ceremony for the first time. During the hybrid event, the winners of the dissertation award were honored in person at the Deichmann Auditorium.
The first award 2021 went to Dr. Maike Elisabeth Lindemann. Her dissertation, "Development and evaluation of new methods to extend the clinical application spectrum of PET/MR hybrid imaging" was supervised by ELH director Prof. Dr. Harald H. Quick. Dr. Lindemann concluded the dissertation to "Dr. rer. medic" with "summa cum laude" on November 4, 2020, and is working as a postdoc in the department "High Field and Hybrid MR Imaging" in the research group of Prof. Dr. Harald H. Quick.
The research group "Experimental Neurology" of ELH-PI Prof. Dr. Dagmar Timmann-Braun is one of the recruiting centers for an international research project on ultra-high field MRI. The project, "Spinocerebellar ataxias: Advanced imaging with ultra-high field MRI (SCAIFIELD)," coordinated by Prof. Tony Stöcker at the German Center for Neurodegenerative Diseases (DZNE) in Bonn, is scheduled to run for three years.
The aim of the project is to optimize the use of ultra-high field MRI for imaging the cerebellum and its structures, and thus for detecting pathological changes in spinocerebellar ataxias. The newly installed 7 Tesla ultra-high field MR system at the ELH will also be included in the project. With its high field strength and excellent soft tissue contrast, it can provide high-resolution images of the human body.
Things happen at the ELH all the time, but not everything is worth a news item on the homepage or even a press release. For the smaller (and larger) news, the ELH has recently started tweeting. Under the handle @ELH_Institute we now report on the everyday life of a research institute.
Curious? Follow us here: https://twitter.com/ELH_Institute
ELH-PI Prof. Dr. Dr. h. c. Onur Güntürkün has been admitted to the Berlin-Brandenburg Academy of Sciences.
The award-winning biopsychologist became a new full member of the Berlin-Brandenburg Academy of Sciences and Humanities in June 2021. As one of his many scientific endeavors Prof. Dr. Dr. h. c. Onur Güntürkün is the project leader of the SFB 1280 "Extinction Learning", in which Prof. Dr. Timmann-Braun's ELH research group is also involved.
The Berlin-Brandenburg Academy of Sciences and Humanities currently has 180 full members, 137 released full members, and 68 associate members. The Academy elects its members from all over Germany, but also from abroad.
Interested in joining our team? We have a vacancy for the position of RF Lab Manager (PostDoc) at the Erwin L. Hahn Institute. We look forward to your application!
The Erwin L. Hahn Institute for Magnetic Resonance Imaging, or ELH, has a new 20-ton core: an ultra-high-field magnetic resonance scanner from Siemens Healthcare (MAGNETOM Terra) with a magnetic field strength of 7 Tesla. From now on, the scanner will be available for the various research groups at the ELH.
The new scanner has already set a record: Only five and a half months passed between commissioning and the delivery of the new 7 Tesla MRI system. Due to fortunate circumstances waiting time was shortened by quite a bit, so that the partners involved in the ELH retrofitting process had to work hard to get everything ready on time. The ELH scientists are thus all the more pleased that the new 7T MRI is now ready for business, despite ongoing restrictions due to the Corona pandemic.
There is still some remaining work to be done, but the ELH is heading towards "business as usual" with great strides. While some peripheral devices still need to be reconnected to the scanner, the first scan on humans has already taken place - Prof. Dr. Harald H. Quick, who had acquired the MRI system costing a good 7.5 million euros on behalf of the ELH with funding from the German Research Foundation (DFG), did not miss the opportunity to be the first person receiving a scan.
Compared to the MRI systems with 1.5 and 3.0 Tesla field strength used in clinical imaging worldwide today, the 7 Tesla UHF MRI system provides a much higher sensitivity for measurements in the human body. This allows cross-sectional images with excellent soft tissue contrast and very high detail resolution.
The new MRI scanner at ELH is faster and more powerful than its predecessor, despite having the same field strength, thus ensuring that scientists on site can continue to conduct cutting-edge research in the future. Unless other restrictions apply due to the Corona pandemic, this should be possible again in the near future (subject to compliance with hygiene and distancing regulations of course).
On November 3rd, the new MRI scanner will be presented and officially inaugurated during the annual Erwin L. Hahn Workshop & Lecture.
In 2020, like everywhere else in the world, the COVID-19 pandemic also held the Erwin L. Hahn Institute firmly in its grip. Most research work had to be suspended or could only take place with considerable difficulties. In addition, the annual Erwin L. Hahn Workshop & Lecture had to be cancelled, much to our regret.
However, despite the negative consequences of COVID-19, the scientists of the Erwin L. Hahn Institute were not idle, and so in this Annual Report we look back on the achievements of the past year and present an optimistic view of the future.
We hope that you are doing as well as possible in this difficult situation and hope to welcome you back to our institute and to the Erwin L. Hahn Lecture soon.
Find the Annual Report 2020 [here].
On June 1st, 2021 saw the launching of the transnational Marie Skłodowska-Curie Training Network (ITN) "Cerebellum & Emotional Networks (CEN)". ELH-PI Prof. Dr. Timmann-Braun played a leading role in the successful application of the ITN and is the deputy network spokesperson.
Two projects of her working group are being carried out at ELH. The aim of the network is to better understand the importance of the cerebellum for emotional control, a task of the cerebellum that has been little understood so far.
The network is supported with a total of 4.5 million euros and is intended to promote international cooperation between scientists and especially young researchers. A total of 15 PhD positions are currently being filled. Interested applicants can apply via the CEN website (link: https://cenproject.blogs.bristol.ac.uk/ ).
Further informationen: [Link]
The German Research Foundation (DFG) has approved the second funding phase for the SFB 1280 (collaborative research centre 1280) "Extinction Learning", in which researchers from the RUB, the University of Duisburg-Essen, the Philipps University of Marburg and the Leibniz Institute for Human Factors Research at the Technical University of Dortmund Ifado are participating. Among other things, the SFB 1280 wants to know how and under what external influences the human brain "stores" memories, or forgets them.
Prof. Dr. Timmann-Braun, Prof. Dr. Harald H. Quick and Prof. Dr. Dr. h. c. Onur Güntürkün from the Erwin L. Hahn Institute for MRI are among those working on this exciting project. Already in the first funding period, the 7 Tesla MRI played a fundamental role in acquiring relevant measurements of the human brain.
The scientists of the SFB 1280 have set themselves ambitious goals for the second funding period: "In our research, we want to comprehensively understand the mechanisms of extinction learning, from genes to the brain to behaviour," explains spokesperson Prof. Dr. Dr. h. c. Onur Güntürkün.
During the first funding period, the scientists were able to show that what humans learn is often not erased from the brain; in fact, we forget much less than we think. Instead, a second memory is established that inhibits the memories of the first. Based on these findings, the team wants to develop new therapeutic options for patients suffering from anxiety disorders or chronic pain.
For this to succeed, further studies and measurements are necessary, a big portion of which will once again take place at the ELH.
Prof. Dr. Dr. h. c. Onur Güntürkün
Fakultät für Psychologie
Tel.: +49 234 32 26213
What a year it has been!
Having had to cancel the Erwin L. Hahn Lecture last year due to the pandemic, we are delighted that the event will return for its 14th edition in 2021 on November 3rd!
With more and more people being vaccinated world-wide, we remain hopeful that this year’s Erwin L. Hahn Workshop & Lecture will be able to happen face to face in person at the OKTOGON/Welterbe Zollverein.
However, should this not prove to be a feasible option in lieu of health and safety regulations come autumn, we will host an online symposium or hybrid-event instead.
We would therefore kindly invite you to join us for our 14th Erwin L. Hahn Workshop and Lecture on November 3rd!
We are delighted to confirm that keynote speaker Prof. Dr. Oliver Speck from the Otto-von-Guericke University Magdeburg has agreed to join us this year, and will talk about "High resolution structural and vascular MR imaging at 7T". As always, a series of thematically related workshops by various speakers will round off the event.
Registration is now open: https://hahn-institute.de/de/hahn-lecture (Participation is free of charge, but we do kindly ask that you register beforehand.) The full programme will be available on the website soon.
Further updates on whether the Erwin L. Hahn Worksop & Lecture will be a physical or digital event will follow as we receive more information.
We hope to see you in November!
Are all 7 Tesla scanners created equal? Do different models give approximately equivalent results, and what does that mean for scientific research and clinical diagnostics? Those were some of the questions that Maximilian Völker and Dr. Oliver Kraff sought to answer in their “Traveling Heads 2.0” study, the results of which have now been published in the renowned journal “NeuroImage”.
A total of ten 7 Tesla MR sites participated for this endeavour, in which identical scan protocols were run at each site on two test subjects, which equally remained the same,, and the results compared. Consequently, for the first time it was also possible to have three different generations of 7 Tesla models “compete” directly against each other. To everyone’s delight the study showed a high reproducibility of quantitative data at the participating 7 Tesla sites.
The scientists hope that these results have laid the foundation for broader scientific studies with multiple participating institutions, which in turn would provide entirely new possibilities for medical research.
The paper can be downloaded here: https://doi.org/10.1016/j.neuroimage.2021.117910
As every year, the Erwin L. Hahn Institute for MRI once again has compiled all significant research results and news from the previous year in its Annual Report, which we are delighted to present. The Annual Report has now been added as a PDF-file to our website, and can be viewed here. [Link]
As of yesterday, the Erwin L. Hahn Institute has a new heart: After the old 7 Tesla MRI scanner’s departure in July, its long-awaited successor moved in yesterday. The new scanner also boasts a field strength of 7 Tesla, but is able to work more efficiently.
Getting the 20 ton-MRI scanner to its new place was a precision job, which was preceded by months of reconstruction work inside the ELH’s premises to ensure both the workers’ and the scanner’s safety.
Full press release at the University of Duisburg-Essen website: https://www.uni-due.de/2020-08-05-supermagnet-fuer-superforschung
For fourteen years the 7 Tesla MRI Scanner was the heart of the ELH institute. However, with over 5,500 scans under its belt, it was time for the ELH to bid farewell to its trusted 7 Tesla.
But what sounds like a sad affair is actually a reason to celebrate: At the end of 2019, the Deutsche Forschungsgemeinschaft (DFG) decided to fund the acquisition of a newer, better 7 Tesla MRI scanner, which will probably move into the ELH at the beginning of August.
We are expecting to get the new scanner up and running by October, and we are excited to be the home to the strongest magnet in the Ruhr area once more.
Photo: (c) Marcel Gratz
The ELH is looking for a postdoc to fill an open position with focus on MRI research and prostate cancer. Experience with MR technology is required.
You can find more details here.
We have some pictures from the Erwin L. Hahn Workshop & Lecture to our websites. In case you couldn't make it this year, or are thinking about joining us next year, check out the link.
How do neural systems adapt to change, and how can MRI help understanding it? These and other questions were the main focus at the 13th Erwin L. Hahn Lecture and Workshop which took place on November 6th on the grounds of the Welterbe Zollverein.
Encouraged by the cozy atmosphere the around 100 participants listened to talks by national and international scientists. The one-hour Erwin L. Hahn Lecture was given by Professor Dr. Heidi Johansen-Berg from the University of Oxford, who discussed studying plasticity and connectivity in the brain with MRI. The Erwin L. Hahn Institute Award for Young Scientists was awarded to Dr. Stefan Rietsch for his PhD thesis "Development and Evaluation of Radio Frequency Antennas for 7 Tesla Ultrahigh-Field Magnetic Resonance Imaging”.
We were delighted by the positive feedback we received for the event and trust you all had a smooth journey home. See you all 2020 for the 14th Erwin L. Hahn Lecture & Workshop!
What better time of the year to carve pumpkins into scary patients? Once again pupils from the Eichendorff-Schule visited the Erwin L. Hahn Institute for MRI. Just in time for Halloween, the children joined staff member Dr. Oliver Kraff to carve their pumpkins, then fill them with fruits and study them using the 7 Tesla MRI scanner. A printed scan from each participant's pumpkin rounded the event off.
Everyone enjoyed themselves and we hope that the discharged pumpkin patients were well enough to spread scary-coziness on the doorsteps for a long time. We are looking forward to next time ...!
This year, the Erwin L. Hahn Institute for Magnetic Resonance Imaging joined institutions nationwide for the “Türöffner-Tag”, organised by “Die Sendung mit der Maus” and opened its doors to the public to answer questions regarding magnetic resonance imaging, and demonstrate just how exactly it works. For instance, what does magnetism have to do with MRI in the first place, and what generates the noise during scanning?
The experiments were enjoyed by children and parents alike, causing much laughter and awe. Afterwards it was time to see the MRI-scanner at work. A pumpkin stuffed with vegetables and fruits posed as a patient so the children and parents could experience first-hand just how exactly the scanning process works.
This was followed by a quiz so everyone could show what they had learned, and afterwards, each participating child received a certificate naming them a “magnetism investigator”.
The ELH would like to thank everyone who came to visit us, participated in the experiments and asked ask us questions. We had a fantastic time, and we hope so did you.
We would like to invite you to join us for the 13th edition of the Erwin L. Hahn Lecture & Workshop on November 6th 2019. This year’s workshops and lecture are dedicated to “Plasticity and Connectivity”, and we are delighted to have Prof. Dr. Heidi Johansen-Berg as our keynote speaker, who will be talking about “„Studying connectivity and plasticity in the human brain with MRI”. The full programme is available here.
Participation is free of charge, but we kindly ask that you register in advance.
On August 28-30, 2019, ELH scientists Dr. Oliver Kraff and Dr. Stephan Orzada will join the ESMRMB workshop „RF simulation for MR systems: Coil design and safety” as faculty members. The workshop will take place in Aachen, Germany. At the moment there are still seats available. Register via the ESMRMB website.
Goals of the course
The course ‘RF simulation for MR systems: Coil design and safety’ is designed to give an in-depth introduction to the numerical computation of radio-frequency (RF) fields in magnetic resonance (MR) systems with the main focus on the application to RF coil design and patient RF safety. The course programme includes modules with theoretical lectures, practical exercises as well as hands-on training on the commercial simulation platforms CST Studio Suite and Sim4Life.
After the course, participants will be able to solve typical MR-related field problems with suitable numerical methods and corresponding models, to interpret the calculated field distributions and to perform appropriate post-processing procedures to characterise multi-channel RF transmit coils and to assess the RF safety of patients/volunteers under consideration of common exposure scenarios.
The course is intended for MR physicists, engineers, other scientists and PhD students who either wish to start working in the field of RF coil development and/or RF exposure or who already have basic to intermediate experience in RF simulation.
The course takes place within the Lectures on MR programme of the European Society for Magnetic Resonance in Medicine and Biology (ESMRMB)
For further information on the course program and registration for the workshop please click here (https://www.esmrmb.org/education/lectures-on-mr/).
Safety and possible clinical applications of 7 Tesla MRI – one of the many research topics that the scientists at the Erwin L. Hahn Institute study. Recently Prof. Dr. Harald H. Quick and Dr. Oliver Kraff received an award from the Wiley Online Library, as between 2017 and 2018 their publication "7T: Physics, safety, and potential clinical applications” (originally published in the Journal for Magnetic Resonance Imaging) was among the top downloaded papers, proving again the high level of research carried out at the ELH. This is a fantastic success for the ELH and the involved scientists.
The Wiley Online Library offers its members access to over 4 Million articles, 14,000 books as well as protocols etc. from almost every possible scientific field.
The digital version of the Erwin L. Hahn Institute’s Annual Report is now available for download here.
The Annual Report is published each spring and allows insights into the scientific work at the institute. While the main focus lies on research done in 2018, the report also includes information on current grants and publications, as well as impressions from the Erwin L. Hahn Lecture.
On February 15th pupils from grade one to four from the Eichendorffschule in Essen-Schönebeck visited the ELH to learn about magnetism and how it is used in magnetic resonance imaging. As with the successful WissensNacht Ruhr last autumn, there were plenty of opportunities to experiment with magnets and see their effect first-hand. Naturally “Mr Pumpkin” once again generously agreed to be scanned by the children with the institute’s 7 Tesla MRI Scanner. The event was a joined effort by the Eichenspatz and the ELH.
Founded in 2007, Eichenspatz is an initiative by the Eichendorffschule’s parents’ association that strives to organise various activities for the children. The ELH was delighted to host the children this year and will be happy to welcome them again next year.
Even in the 21st century it is still possible to find new anatomical structures within the human body – with the help of UHF MRI. Scientists from the Institute for Experimental Immunology and Imaging from the Medical Faculty of the University of Duisburg Essen lead by Professor Matthias Gunzer were able to detect a previously unknown system of blood vessels in murine bones. With help of the 7T UHF MRI system at the Erwin L. Hahn Institute indications of these vessels could also be demonstrated in human bones. For this Professor Gunzer showed full commitment and spend multiple hours in the 7T MRI system. This astounding discovery might ultimately help in understanding, for example, how tumours metastasize in the bones.
Press release: here.
Additional information: here.
You rarely get to see it this up close – the strongest magnet in the Ruhr area. For the third edition of the WissensNacht Ruhr (ScienceNight Ruhr) the Erwin L. Hahn Institute for Magnetic Resonance Imaging once again opened its doors to the public to answer questions regarding magnetic resonance imaging, and demonstrate just how exactly it works. For instance, what does magnetism have to do with MRI in the first place, and what generates the noise during scanning?
The Helene-Keller-Schule’s 3rd graders made for an early start and dropped by in the morning to take a look at the scanner ad test out the various magnetism-related experiments provided by the ELH.
The experiments were enjoyed by children and parents alike, causing much laughter and awe. Afterwards it was time to see the MRI-scanner at work. A pumpkin stuffed with vegetables, fruits and Kinder Surprises was scanned and the children encouraged to guess which items would show up how on the screen.
This was followed by a quiz, for which the group was split into two equally enthusiastically teams. In the end, each participating child received a certificate naming them a “magnetism investigator”. Finally, the talk aimed at a grown-up audience later that night was also well attended, and followed by a guided tour to the MRI scanner.
The ELH would like to thank everyone who came to visit us, participated in the experiments and asked ask us questions. As you may find in the impressions of this day, we had a fantastic time, and we hope so did you.
Past Wednesday, members of medicine, science and industry gathered for the 12th Erwin L. Hahn Workshop & Lecture to discuss the pros and cons of ultra-highfield magnetic resonance imaging.
Hosted in the conference room of the CASINO Zollverein, workshops and coffee breaks alike were welcome opportunities for networking and catching up with fellow participants. The workshop featured talks by both national and international guests. For the Hahn Lecture, we were honoured to welcome Prof. Dr. Klaus Scheffler from the Max Planck Institute for Biological Cybernetics, who talked about the pros and cons of human brain imaging at 9.4 Tesla.
We would like to thank all the contributors and participants who made the event an all-around success. We hope to see you again in 2019 for the 13th Erwin L. Hahn Workshop & Lecture!
Whether it’s a stroke, a myocardial infarction, preneoplasia or other affections of the body – in hospital routine an MRI scan is often crucial for literally visualising the insides of a human body, and diagnosing the patient. The more detailed and high-resolution the images delivered by the scanner, the better.
Two junior scientists from the Erwin L. Hahn Institute for MRI were now awarded for their research work at the ELH. Laureates are Stefan Rietsch, who received the DGMP’s Young Investigator Award for his contribution „Evaluation einer 8-Kanal-Sende/32-Kanal-Empfangsspule für die 7T MRT im Körper“ and Sascha Brunheim, who placed second at this year’s Gorter Award. The Gorter Award is presented to junior scientists for an outstanding contribution in medicine or science.
Both awardees from Prof. Dr. Harald H. Quick’s group “High Field and Hybrid MR Imaging” are developing new methods of 7 Tesla Ultra-Highfield-MRI at the ELH. The research focuses on the development of new 7T UHF-applications with high resolution for human body imaging.
Which benefits does ultra-highfield-MRI offer, and what are the challenges that higher field strengths pose for scientists and clinicians alike? These are only some of the questions that this year’s Erwin L. Hahn Workshop & Lecture seeks to answer. Themed “7T and Beyond” the event takes place on October 10th, 2018 on the grounds of the World Heritage Site Zollverein. We are delighted to have Prof. Dr. Klaus Scheffler from the Max Planck Institute for Biological Cybernetics as our keynote speaker. His talk will focus on the pros and cons of 9.4 Tesla MRI.
Participation is free, registration is open NOW. More information here.
ELH staff member Dr. Stephan Orzada has been appointed editor at the open access journal PLOS ONE. Starting immediately, all MR-hardware related submitted articles will be viewed by Stephan Orzada, who will also have the final decision on whether the contributions will be published in the journal.
PLOS ONE is an interdisciplinary online scientific journal initiated by Nobel Prize awardee Harold Varmus. It ensures the article’s quality by making use of peer reviewers, and is one of the best known multidisciplinary scientific journals.
What is an MRI scanner? What is it used for, and why is it so important for hospitals? Come and find out!
If you are between 6 and 13 years old, we invite you to join us for the 3rd WissensNachtRuhr on September 28th at the Erwin L. Hahn Institute. Starting from 4pm you will get the chance to conduct various magnetism experiments, and of course also witness the scanner – the strongest magnet in the Ruhr area - in action. Adults won’t have to miss out either – there will be a presentation on ultra-high field MRI later in the evening.
Details on programme and registration soon.
Same procedure as every year: Earlier this month, the Erwin L. Hahn Institute for MRI released its Annual Report 2017, which is now also available online. The report includes contributions on the full range of applications at 7T: from hardware development to applications of spectroscopy, and from imaging the brain to the prostate.
Also included are, among other things, some impressions from the 11th Erwin L. Hahn Lecture as well as a list of publications and awards received by ELH staff members.
The Annual Report can be downloaded here.
How cerebellar and cerebral areas are activated during acquisition, extinction and reacquisition of trace and delay conditioning is what Dr. med. Jens Claaßen will focus on during his one-year IFORES-scholarship at the Erwin L. Hahn Institute. The main aspect of his research is the understanding of how learning processes work. He is joined by IFORES-scholar Dr. med. Oliver Gembruch, who is interested in improved imaging of implicit cerebral aneurysms. His main focus will be the evaluation of the aneurysm wall before and after contrast agent is added, which should help to draw conclusions relating to inflammatory reactions in the aneurysm wall and possible connected rupture risks.
The University Duisburg-Essen strives to encourage networking between the clinical and research departments of the University Hospital, the LVR-Klinikum Essen and the Ruhrlandklinik. Every year up to five internal research scholarships (IFORES) are given to MDs from these clinics, allowing them to do basic-science research for a year.
What would a symposium be without participants? We would like to extend a heartfelt thank you to all the visitors, presenters and our guest speaker Prof. Dr. Christian Büchel, all of whom made the 11th Erwin L. Hahn Lecture the successful event it was.
This year the Hahn Lecture was all about “Clinical Neuroimaging”, offering not only a variety of talks but also plenty of chances to catch up with colleagues. The unique location of the OKTOGON on the grounds of the Zeche Zollverein put the finishing touch on the programme.
A few pictures of the 11th Erwin L. Hahn Lecture can be found here.
When do you ever get the chance to see the biggest magnet in the Ruhr area? The Erwin L. Hahn Institute recently opened its doors for the kids from Stiftung Zollverein’s Holiday Workshop – and invited them to prove themselves as magnetism experts while they were at it.
After a short introduction to magnetic resonance imaging and safety by Dr. Oliver Kraff, the scientists-to-be were eager to start: Which materials are attracted to magnets? Which part of a magnet is the strongest? What is an electromagnet? A series of experiments were set-up to help answer these and other questions.
Then it was time to use the scanner. A Halloween-style carved pumpkin was filled with an assortment of fruits and scanned. From the control room the little guests watched in awe as the images from inside the pumpkin became visible on the computer screens.
To round the visit off, the newly magnetism experts each received their certificate, before they went on their next adventure.
The Hahn Lecture will take place on November 15th on the grounds of the Welterbe Zollverein. Our guest speaker this year is Leibniz-Preis awardee Prof. Dr. med. Christian Büchel from the University Medical Centre Hamburg-Eppendorf.
Participation is free, but please register online in advance!
We are looking for 10 healthy participants (m/f) for a study that aims at developing an MRI method that improves the localization of activation in the brain. The participants should be between 18 and 40 years old.
Since the scan includes a short, undemanding task in which the participants will need to respond to a visual stimulus, moderately good vision is required. It is possible to wear contact lenses inside the scanner.
The total scanning time will be approximately 1 h 30; participants will receive a recompense of 25 Euros for the session.
The measurements will take place at the Erwin L. Hahn Institute between 17th and 26th of August. The exact date and time will be agreed based on the participant’s and scanner availability.
If you are interested, please contact Irati Markuerkiaga: firstname.lastname@example.org
The year 2016 was a very special year for the Erwin L. Hahn Institute in many regards--most notably, we celebrated the ELH’s 10th anniversary. When we officially started in 2006, our 7-Tesla MRI system was only the 6 th in the world operating at this magnetic field strength.
The members of the ELH are therefore delighted to present their Annual Report 2016, in which we take a look back at the past 10 years as well as the 2016 Erwin L. Hahn Lecture, and relate our scientific endeavors and achievements. Also included is a brief remembrance of the late Erwin L. Hahn, after whom our institute is named, and who passed away in September 2016.
The Annual Report is available here.
Over 7,000 “abstracts” – short summaries of science projects, presentations or articles – were handed in for this year’s annual ISMRM conference. Out of these 7,000 abstracts, the best ones were now awarded for excellence—including five from scientists from the Erwin L. Hahn Institute. This is a new record performance for the ELH.
The prize winners are:
Sören Johst for „32-Channel In-Vivo Parallel Transmit Body Imaging at 7 Tesla”
Marcel Gratz for “On the Potential of DWI with Extrapolated High and Negative b-Values for Contrast Enhancement and Image Segmentation”
Stephan Orzada for „ A 32-channel transmit system add-on for 7 Tesla body imaging”
Sascha Brunheim for “Fast Multi-Slice B1 and B0 Mapping (B01TIAMO) for 32-Channel PTx Body MRI at 7 Tesla”
Nicolai Spicher for „An open-source hardware and software system for video gated MRI”
Every year the ISMRM (International Society for Magnetic Resonance in Medicine) invites their members from all over the world to join them for their annual conference to discuss their research and experiences. This year, the conference will take place in Honolulu, Hawaii. About 20 ELH scientists will be on site, bringing with them a total of almost 30 presentations, posters and panels.
The Erwin L. Hahn Institute, located on the grounds of the Kokerei Zollverein in Essen, is looking for 100 participants for a study about obesity and cognition.
In an earlier study it was revealed that patients diagnosed with type 2 diabetes show a higher GABA concentration in their brain. GABA is a neurotransmitter that is involved in the “communication” between neurons and consequently in cognitive processes.
The scientists at the ELH are now conducting a new comprehensive study to assess whether higher GABA-levels correlate only with type 2 diabetes, or whether they are linked to obesity in general. The results could provide important data for hospital routine.
Starting immediately, we are looking for participants (m/f) between the age of twenty and early thirties, who are willing to serve as test subjects. To provide a large range of normal-weight and overweight subjects, interested participants should have a BMI (Body Mass Index / weight divided by height in meters squared) between 18,5 and 35.
In addition to undergoing an MRI scan the subjects will have to take some cognitive psychology tests regarding memory, attention etc. These tests will be taken at a computer and/or with printed sheets. The study will take between 2 hours per subject and will be remunerated with 50€.
You will not be exposed to harmful radiation or dangerous substances!
Interested? Contact us via:
phone: 0201 183 6067 || email@example.com
More than 60 MRI-scanners with a field strength of 7T and above are installed worldwide – and the number is rising. These days, UHF-MRI is exclusively used in scientific research, while hospitals still work with weaker scanners at 1,5 or 3 Tesla. It goes without saying that the long-term aim is to make UHF-MRI with its high-resolution imagining feasible for the hospital routine.
In their article „7T: Physics, Safety, and Potential Clinical Applications“ Professor Dr. Harald H. Quick and Dr. Oliver Kraff from the Erwin L. Hahn Institute discuss the current state of affairs, the problems UHF-MRI yet has to face and what progress has been made in recent years. The article was published in the Journal of Magnetic Resonance Imaging by the “International Society for Magnet Resonance in Medicine”.
Some pain we feel immediately, some we can consciously ignore or even suppress for a long time. The processes behind this phenomena is what the Dutch physicist Dr. Peter Koopmans and his research group are interested in. With the help of the ELH’s 7T MRI scanner, they hope to improve the procedure of imaging the cortical layers and ultimately produce unparalleled pictures of the human brain.
The research group is funded by the DFG’s (Deutsche Forschungsgesellschaft) Emmy Noether-Programme, and part of professor Quick’s research group “High Feld and Hybrid MR Imaging” at the University Hospital Essen.
The official press release can be found here: https://www.uni-due.de/de/presse/meldung.php?id=9768
Just before Christmas the Erwin L. Hahn Institute for Magnetic Resonance Imaging received some good news: Based on the successful first funding phase the DFG has granted the German Ultrahigh-Field Imaging (GUFI) network an additional allowance of €355,000 until 2020.
The official press release can be found here: https://www.uni-due.de/de/presse/meldung.php?id=9724
Astrid Rosenthal-von der Pütten from the Erwin L. Hahn Institute will be one of the key speakers at the upcoming Media Neuroscience symposium on March 3rd and discuss how and if Likes on Facebook serve as social rewards.
Media Neuroscience is a research field at the intersection of Communication Studies, Media Studies and Neuroscience. How do we react towards robots? What happens in our brains when we watch a movie? The symposium, organized by the Global Young Faculty, aims to answer these and more questions.
The symposium offers the possibility to explore current topics in the emerging interdisciplinary field of Media Neuroscience and address an agenda for future research.
Location: Gerhard-Mercator-Haus at University of Duisburg-Essen
Admission is free, though registration (until February 17th) is required: http://global-young-faculty.de/medianeuro/
In the course of multiple studies for the Global Young Faculty we are looking for study participants who frequently use Facebook and (at least occasionally) post selfies to it.
… will take place at the laboratory in Duisburg (Campus Duisburg, LE Building, LE202). This study will take up about 1.5 hours (15 Euros or 1.5 VP hours for Komedia and Psychology students). The appointments will be scheduled between 8th and 10th February 2017.
…is a neuroscientific study. It will require about 4 hours of your time, out of which you will spend approx. 1.5 hours inside the “tube”, an MRI scanner (40 Euros or 4VP hours for Komedia and Psychology students). For the survey period between 17th and 21st February 2017, we are looking for male participants only. For the dates in April (we are anticipating 24th to 28th April), we are looking for both female and male participants. The study will take place at the Erwin L. Hahn Institute for Magnetic Resonance Imaging on the Kokerei Zollverein (World Heritage Site Zollverein) in Essen. The procedure is neither harmful nor painful, and you will not be subject to radiation. You must be at least 18 years old.
Interested? Simply send an email to firstname.lastname@example.org and indicate which study you would like to participate in (Selfie Lab or Selfie fMRT).
You will receive all further information as well as the date and time by email.
We’re looking forward to hearing from you!
Thanks to everyone who celebrated 10 years of ultrahigh field MR research at the Erwin L. Hahn Institute on October, 5th, 2016 with us and helped making the 10th Erwin L. Hahn Lecture a memorable event for our guests as well as the members of the institute.
You can find some impressions from this special day on the event page.
The ELH participated in a Holiday-Workshop offered by the Zollverein Coal Mine. 19 children in the age of 10 to 14 experimented on October 11th and October 18th at the ELH, tried to evaluate MR images and were awarded as Magnetism-scientists.
The Research Report of the University of Duisburg-Essen presents the main research areas and selected research institutes with their research foci in the last two years. The contribution about the Erwin L. Hahn Institute can be found via https://www.forschungsbericht.uni-due.de/en/content-2015/content-2015/erwin-l-hahn-institute-for-magnetic-resonance-imaging/ and on our Research reports page. We hope you enjoy reading it.
Erwin L. Hahn, after whom our institute was named, died on September, 20th 2016. Here you can find the official obituary.
We were happy to welcome such enthusiastic and interested children and adults in all items of our program!
Erwin L. Hahn, after whom our institute was named, died on September, 20th 2016 at the age of 95.
He made many valuable contributions to the field of magnetic resonance imaging. He became famous for detecting the spin echo, which is one of the basic methods of signal generation in magnetic resonance imaging.
Those of us, who had the luck to be present at his visit to our Institute in 2009, were deeply impressed by this outstanding scientist and in particular by his very inspiring, motivating and humorous nature.
We are proud and honored to perpetuate his memory by continuing ultra‐high field MRI research in his name.
This year, the Erwin L. Hahn Institute celebrates 10 years of research in the field of magnetic resonance imaging at the site of the world cultural heritage Zeche Zollverein.
At the Erwin L. Hahn Institute physicists, engineers, medical scientists and psychologists work hand in hand. The interdisciplinary collaboration of internationally staffed research teams enables the institute to cover large areas of ultrahigh field MRI research: the development of new hardware and methods, its application in cognitive sciences and the transfer into early clinical applications.
Equally wide-ranging are the research areas of the keynote speakers of this year's 10th Erwin L. Hahn Lecture on October, 5th.
The invited 7 leading experts in the field of MR will present interesting insights into the history and in particular into future potentials of ultrahigh field MR.
The event starts at 10 am at the Erich-Brost-Pavillon, Zeche Zollverein.
This year the Erwin L. Hahn Institut will take part, when the Ruhrgebiet is transforming to a huge research lab during the WissensNacht Ruhr on 30th September.
Our younger guests (6 to 13 yrs) can join at 4pm, 5:30pm and 7pm to answer their questions on the topic of magnetic resonance tomography (short: MRI) and its impact and application in medicine. With the help of small experiments magnetism and its impact can investigated. Furthermore, we will scan objects with our whole-body MRI.
How does a magnetic resonance tomograph actually work? What can we see on the images? Which safety measures have to be taken into account? These and even further question will be answered by our local experts starting from 8:30pm and 9:15pm, who moreover will allow you to visit our research device with the strongest magnet in the whole Ruhrgebiet. During some overview talks we will show you which advantages such a strong magnetic field has and which challenges have to be overcome by our researchers.
For further information refer to www.wissensnacht.ruhr.
You will need to register to participate.
The ELH welcomes students and supervisors of the graduate school 1739 on cellular response to ionizing radiation from the University Hospital Essen for a methods seminar on magnetic resonance imaging. Participants will learn basics of MR physics, hardware and imaging sequences. Afterwards a hands-on session at the 7 Tesla MRI system will complete the seminar.
Das Erwin L. Hahn Institut ist auch dieses Jahr wieder einer der Spielorte der Extraschicht am 25. Juni 2016. Auf dem geschichtsträchtigen Gelände der Kokerei des UNESCO-Welterbes Zeche Zollverein öffnet das Institut dem interessierten Publikum seine Türen.
Im Rahmen von Vorträgen bietet sich die Möglichkeit, Interessantes und Wissenswertes rund um die 7 Tesla-Ultrahochfeld-Magnetresonanztomographie und die Forschung am Erwin L. Hahn Institut zu erfahren. An einem Quizstand können die Besucher ihr Wissen in diesem Themengebiet testen.
The ELH proudly announces the publication of 3 studies in the topical Special Issue on "Ultrahigh Field MR: Cutting Edge Technologies Meet Clinical Applications" in the journal of Magnetic Resonance Materials in Physics, Biology and Medicine (MAGMA, http://link.springer.com/journal/10334/29/3/page/1), which ranks among the top 30 journals in the field of imaging/radiology. The articles are from Bixia Chen regarding “Cranial fixation plates in cerebral magnetic resonance imaging: a 3 and 7 Tesla in vivo image quality study”, Maximilian Völker with his multicenter study “The traveling heads: multicenter brain imaging at 7 Tesla”, and Oliver Kraff investigating “7 Tesla quantitative hip MRI: a comparison between TESS and CPMG for T2 mapping”.
The development of ultrahigh field magnetic resonance (UHF-MR) is moving forward at an amazing speed that is breaking through technical barriers almost as fast as they appear. UHF-MR has become an engine for innovation in experimental and clinical research. With almost 40,000 MR examinations already performed at 7.0 Tesla, the reasons for moving UHF-MR into clinical applications are more compelling than ever. The ELH is delighted to have continuously contributed to this research for the past 10 years.
Please mark your calendars now for the 10th Erwin L. Hahn Lecture and Workshop on October, 5th, 2016.
We cordially invite you to attend this special event and celebrate 10 years of ultrahigh field MR research at the Erwin L. Hahn Institute in the Erich-Brost-Pavillon of the UNESCO World Heritage Zollverein in Essen.
As you can find in detail in the flyer, the program will include 7 main talks of leading experts in the field of MRI and a poster session.
Please feel free to circulate the invitation among colleagues potentially interested in this conference.
Participation is free.
On October 5th, registration will open at 9:15 am, talks will start at 10:00 am. The last talk is expected to finish at 5:00 pm, afterwards there will be some time for discussion.
Congratulations to Dr. Oliver Kraff for being elected as Trainee Representative for the ISMRM MR Safety Study Group!
His post will begin during the upcoming 2016 ISMRM Annual Meeting & Exhibition in Singapore and end after one year.
Congratulations to Miriam Lagemaat and Eline Vos for their successful theses defenses!
Title of Miriam Lagemaats thesis is "1H and 31P Spectroscopic Imaging of the Prostate at 7 Tesla", promotors were Prof. Dr. Arend Heerschap, Dr. Tom Scheenen und Dr. Marnix Maas (Radboud UMC). Eline Vos thesis is entitled "Magnetic resonance imaging of prostate cancer: assessment of aggressiveness and pre-clinical developments" and has been promoted by Prof. Dr. Jelle Barentz and Dr. Tom Scheenen.
In order to gain a personal impression of the successful Dutch-German research collaboration, the Commissioners of the king of the provinces of Gelderland and Overijssel, Clemens Cornielje and Ank Bijleveld, visited the institute on November, 13th. Franz-Josef Lersch-Mense, the NRW Minister for Federal Affairs, Europe and Media, accompanies them. The visitors were deeply interested in the institute and the research activities. Highlight of the institute tour was the visit of the heart piece of the institute, the 7 Tesla MRI scanner.
Photos: Dave Kittel, Medienzentrum Uniklinikum Essen
During the Erwin L. Hahn Lecture on October, 7th, 2015 Dr. Sören Johst has been awarded with the Erwin L Hahn Institute award for young scientists for his excellent Ph.D. thesis "Acquisition Methods for 7 Tesla MRI from Head to Toe" published in 2014.
Congratulations to Nicolai Spicher, who was awarded with the "Förderpreis der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie" for his extraordinary thesis Ultra High-Field MRI: Implementation and Evaluation of the Eulerian Video Magnification for peripheral pulse triggering on the 60th GMCS Meeting 2015 in Krefeld.
Beim 2. Welterbelauf auf Zollverein am 12. September waren dieses Mal auch Läufer vom ELH am Start. Stefan Rietsch liess bereits in der ersten Runde seine Kollegen weit hinter sich und schaffte die 5 km Strecke über die Kokerei in einer Topzeit von 22:56 Minuten. Er belegte damit Platz 36 ( Platz 11 in seiner Altersklasse). Nur wenig später kam Harald Quick mit einer Zeit von 24:19 Min. auf Platz 52 (11 in der Altersklasse) durchs Ziel. Hervorzuheben sind zudem Bixia Chen, die mit 25:32 Min. den 13. Platz, jedoch Platz 2 (!) in der Alterklasse belegte, sowie Katharina Hauprich, die mit 26:58 Min. Platz 23 in der Gesamtwertung und Platz 6 in der Alterklasse belegte. Ebenfalls unter den Top 10 seiner Alterklasse war Oliver Kraff, mit einer Zeit von 26:15 Min. auf Platz 88 (9 in der Altersklasse). Maximilian Völker räumte das Feld von hinten auf und legte mit einer Zeit von 29:04 Min. auf Platz 129 bzw. 14 in seiner Alterklasse gleichfalls einen klasse Lauf hin.
It is a pleasure to announce that Yacine Noureddine's first paper entitled "Experience with magnetic resonance imaging of human subjects with passive implants and tattoos at 7 Tesla: a retrospective study", has just been accepted for publication in Magnetic Resonance Materials in Physics, Biology and Medicine (MAGMA). Congratulations!
Congratulations to Gregor and Yasmin Zaun, who were awarded with the "Promotionspreis" of the medical faculty for their extraordinary dissertations Effekte starker statischer Magnetfelder auf die Spermatogenese und männliche Fertilität im Mausmodell (Gregor Zaun) and Auswirkungen starker statischer Magnetfelder auf die weibliche Reproduktion und die Fertilität im Mausmodell (Yasmin Eschrat Zaun, geb. Zahedi).
Starting from June, 20th the access to Erwin L. Hahn Institute via Arendahls Wiese and Heinrich-Imig-Street will be possible again.
Due to road words on "Im Welterbe" you can not reach ELH via Großwesterkamp by 22nd june.
Am Universitätsklinikum Essen wird nicht nur intensiv zur Hirnentwicklung Frühgeborener geforscht, sondern auch zur Rolle des Kleinhirns bei Denkprozessen. Das Verständnis dieser Prozesse soll dazu dienen, sehr kleine Frühgeborenen in Zukunft besser behandeln und in ihrer Entwicklung unterstützen zu können. In dem Zusammenhang startet eine neue Studie am ELH in Kooperation mit der Klinik für Kinderheilkunde und der Experimentellen Neurologie am Universitätsklinikum Essen, deren Ziel es ist herauszufinden, in welcher Weise die Frühgeburtlichkeit Einfluss auf die Entwicklung des Kleinhirns und seiner Strukturen hat. Hierfür werden Probanden gesucht, die zwischen 18 und 25 Jahre alt sind und als Frühgeborene zur Welt kamen. Weitere Informationen gibt es im FLYER und unter http://www.uk-essen.de/ab-durch-die-roehre/.
Oft sind es Autounfälle, bei denen der Kopf durch abruptes Bremsen verletzt wird: Schädel-Hirn-Traumata – medizinisch: axonale Scherverletzungen – erleiden rund 270.000 Menschen pro Jahr. Bei etwa einem Drittel dieser Hochrasanz-Traumen lassen sich die schweren Hirnverletzungen jedoch bislang nicht nachweisen. Wissenschaftler der Medizinischen Fakultät der Universität Duisburg-Essen (UDE) am Universitätsklinikum Essen (UK Essen) und des Erwin L. Hahn Instituts für Magnetresonanz (ELH) haben nun erstmals den diagnostischen Einsatz eines 7 Tesla Magnetresonanztomographen (MRT) für diese Fragestellung untersucht. Sie berichten davon im Fachmagazin Plos One.
Die Kosten für das deutsche Gesundheitssystem zur Versorgung Schädel-Hirn-Verletzter werden auf 2,5 Milliarden Euro jährlich geschätzt. Ausgelöst wird ein solches Trauma zum Beispiel durch Verkehrsunfälle, Stürze aus großer Höhe oder Sportverletzungen. Die rasche Be- und Entschleunigung des Hirngewebes lässt Nervenfasern zerreißen und löst Mikroblutungen aus. Anschließend leiden die Patienten unter verschiedenen Symptomen, angefangen bei leichten Gedächtnisstörungen, bis hin zu posttraumatischer Demenz.
Allerdings können nur 72 Prozent dieser schwerwiegenden Kopfverletzungen zweifelsfrei diagnostiziert werden. Bei etwa einem Drittel der Patienten lässt sich keine strukturelle Hirnschädigung nachweisen, obwohl sie unter neurologischen und neuropsychologischen Beeinträchtigungen leiden. Dabei ist die Diagnose für die Rehabilitation, die berufliche Reintegration sowie in versicherungsrechtlichen Fragen entscheidend.
„Bei Verdacht auf ein Schädel-Hirn-Trauma setzt man u.a. auf radiologische Untersuchungen, in der Regel auf die Magnetresonanztomographie“, erläutert Prof. Dr. Michael Forsting, Direktor des Institutes für Diagnostische und Interventionelle Radiologie und Neuroradiologie am UK Essen. Ein neuer Ansatz gibt nun Hoffnung auf Klarheit. In einer Pilot-Studie am UK Essen konnten die Wissenschaftler die Identifikation der traumatischen Mikroblutungen im Gehirn entscheidend verbessern. Sie verglichen dabei die Bilder der üblichen 3 Tesla Hochfeld-MRT mit der mehr als doppelt so starken 7 Tesla Ultrahochfeld-MRT.
Untersucht wurden zehn Probanden mit bekannten Scherverletzungen im Alter von 20 bis 74 Jahren. Die 7 Tesla MRT stellte bei den Betroffenen signifikant mehr traumatische Mikroblutungen in der Hirnsubstanz dar als vergleichbare 3 Tesla-Aufnahmen. Dies führen die Forscher darauf zurück, dass der sogenannte Suszeptibilitätseffekt der Blutabbauprodukte, also ihre Magnetisierbarkeit, mit steigender Magnetfeldstärke zunimmt. Zudem erlaubt die 7 Tesla MRT Aufnahmen des Gehirns in höherer räumlicher Auflösung als es mit klinisch gebräuchlichen MRT-Scannern von 1,5 Tesla und 3 Tesla Magnetfeldstärke möglich ist.
Bisher wird die 7 Tesla MRT nur für Forschungszwecke am Erwin L. Hahn Institut für Magnetresonanz (ELH) genutzt. In weiteren Studien soll nun geklärt werden, ob sich diese nicht auch bei unklaren Fällen von Schädel-Hirn-Traumata einsetzen lässt.
Publikationshinweis: „Diffuse Axonal Injury at Ultra-High Field MRI“ http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0122329
Due to road works it may be impossible to reach the Erwin L. Hahn Institute via Heinrich- Imig- Street by 2015-03-16. Use access via Großwesterkamp Street instead.
Am 25.09.-26.09.2015 findet in der Uniklinik Essen wieder der MTRA-Kongress „Der Pott Kocht“ statt, bei dem auch wieder einige Mitarbeiter aus dem ELH als Vortragende oder im technischen Hintergrund mitwirken.
Was wäre die Medizin ohne Magnetresonanz-Bilder? Einer, der daran forscht, wie sich immer bessere Ansichten aus dem menschlichen Körper gewinnen lassen, ist Prof. Dr. Harald H. Quick von der Universität Duisburg-Essen (UDE). Der Spezialist für Hochfeld- und Hybride MR-Bildgebung hat jetzt den Magnetic Resonance Imaging Award erhalten. Er wird alle zwei Jahre für herausragende wissenschaftliche Leistungen auf diesem Gebiet vergeben.
Quick, der auch Direktor des Erwin L. Hahn Instituts für MR-Bildgebung ist, nahm den Preis auf der "MR 2015 Garmisch" entgegen, der größten deutschen Tagung für Magnetresonanzbildgebung. Der Kongresspräsident übergab ihn mit den Worten, Harald Quick habe sich in den letzten Jahren überall dort eingebracht, wo sich Neuerungen geboten haben. Seine Beiträge zur Entwicklung der Technologie und Methodik, insbesondere auf dem Gebiet der Ultrahochfeld-Magnetresonanz und der Hybriden PET/MR-Bildgebung, seien herausragend.
Das ELH-Team gratuliert von ganzem Herzen Herrn Dr. Sören Johst zur erfolgreichen Verteidigung seiner Dissertation "Acquisition Methods for 7 Tesla from Head to Toe". Die öffentliche Verteidigung fand am 16. Dezember 2014 an der Radboud Universität Nijmegen statt.
7 Tesla high field tomography: imaging in HD
Ultra high field imaging makes extremely high-resolution images possible. But this is not the only advantage in comparison to 1.5 and 3 Tesla tomography. The 7 Tesla MRI supersedes the use of contrast media because it natively provides images in HD quality. Nevertheless, it is only used in research so far. Dr. Lale Umutlu and Prof. Harald Quick want to change that.
We would like to thank all the speakers, in particular Prof. Dr. Arend Heerschap for his great lecture on "MR spectroscopy: from insight to impact", who all made yesterday's Erwin L. Hahn Spectroscopy Workshop and the Erwin L. Hahn lecture 2014 a successful event full of interesting research results and scientific exchange. Also, we would like to thank all people in the background who organized the event and cared for a smooth course of registrations, talks, food and finally drinks.
During the Erwin L. Hahn lecture 2014 Dr. Stephan Orzada has been awarded with the Erwin L Hahn Institute award for young scientists for his Ph.D. thesis "New Excitation Concepts for Ultra-High-Field Human MRI" published in 2013.
This year’s Erwin L. Hahn Lecture will be given by Professor Arend Heerschap of the Department of Radiology and Nuclear Medicine, UMC Nijmegen. Professor Arend Heerschap is well known for his work on both proton and carbon spectroscopy, and in particular for their use in oncology. The Erwin L. Hahn Lecture will be held in conjunction with a complementary workshop examining the latest developments in in vivo spectroscopy and the applications of X-nuclei. You are warmly invited to attend this memorable meeting on October 8th.
Deadline for registration is October 01, 2014.
Jetzt ist es offiziell, wir haben eine neue Adresse: Kokereiallee 7.
Arendahls Wiese 199 und auch Heinrich-Imig-Straße 9 gelten nicht mehr.
European Hospital and Deutsche Röntgengesellschaft e.V. met up with Professor Harald H. Quick, PhD, who was appointed as one of the Directors of the Erwin L. Hahn Institute (ELH) for Magnetic Resonance (MR) Imaging 1st February 2014. Being in charge of highfield and hybrid (MR) imaging, Quick shared his views on the status of and the imminent research into MRI systems operating at 7.0 Tesla (7T) as well as the combined positron emission tomography (PET)/MR hybrid imaging technology.
Gleich zwei Ministerpräsidenten besichtigten am 15. Januar 2014 das Erwin L. Hahn Institut für Magnetresonanz. Auf Einladung seiner NRW-Kollegin Hannelore Kraft informierte sich der niederländische Regierungschef Mark Rutte vor Ort über das erfolgreiche Gemeinschaftsprojekt der Universität Duisburg-Essen mit der Radboud-Universität in Nimwegen.
Die beiden Spitzenpolitiker konnten sich bei ihrem Besuch ein eigenes Bild davon machen, was das grenzüberschreitende Forscherteam leistet. Nach einer Einführung des Geschäftsführenden Direktors Prof. Dr. David Norris besichtigten die Gäste das Herzstück des Forschungszentrums, das 7 Tesla-MRT-Gerät. Dabei konnten sie anhand kleiner Experimente das Magnetfeld sichtbar machen.
Die in der Presse kürzlich vorgestellte Dino-Roboter Studie zur emotionalen Bindung von Menschen zu einem Roboter ist unter dem Titel "Investigations on Empathy Towards Humans and Robots Using fMRI" von Astrid Rosenthal von der Pütten und Kollegen bei Computers in Human Behavior akzeptiert worden. Die Arbeit wird in Kürze online erhältlich sein.
To explore emotionality in human-robot interaction we conducted two studies. In the first study (n = 40) participants saw videos with a robot being treated in an affectionate or in a violent manner (within-subjects factor). Participants reported to feel more negative watching the robot being abused. In a follow-up fMRI study (n = 14) subjects were presented videos showing a human, a robot and an inanimate object, again being treated in either an affectionate or in a violent way. Violent interaction towards both, the robot and the human, resulted in similar neural activation patterns in classic limbic structures, indicating that they elicit similar emotional reactions. However, when comparing only the videos showing abusive behavior differences in neural activity suggest that participants show more negative empathetic concern for the human in the abuse condition. This was supported by similar findings with regard to participant's self-reported emotional states.
It is a pleasure to announce that ELH's recent invited review article "Ultra-High-Field MRI at 7T and Above: Demonstrated and Potential Capabilities" has been accepted for publication in the Journal of Magnetic Resonance Imaging. The review article was a combined work of Oliver Kraff (ELH; first author), Anja Fischer and Christoph Mönninghoff (University Hosital Essen), as well as Armin Nagel and Mark Ladd (DKFZ Heidelberg). The review article will be available online within the next 2 months, approximately.
With more than 40 installed magnetic resonance (MR) systems worldwide operating at 7 Tesla or higher, ultra-high-field (UHF) imaging has been established as a platform for clinically oriented research in recent years. Along with technical developments that, in part, have also been successfully transferred to lower field strengths, MR imaging and spectroscopy at UHF have demonstrated capabilities and potentials for clinical diagnostics in a variety of studies. In terms of applications, this overview article focuses on already achieved advantages for in vivo imaging, i.e. in imaging the brain and joints of the musculoskeletal system, but also considers developments in body imaging, which is particularly challenging. Furthermore, new applications for clinical diagnostics such as X-nuclei imaging and spectroscopy, which only really become feasible at ultra-high magnetic fields, will be presented.
The german research foundation (DFG) has recently approved funding of the research unit "Extinction Learning: behavioral, neural, and clinical mechanisms", encompassing workgroups at the Universities of Bochum, Duisburg-Essen, and Marburg. Extinction learning is a basic behavioral phenomenon in which an organism learns that two events which used to occur jointly have ceased doing so. Unlike acquisition, i.e. original learning, extinction is highly context-specific, which is one of the many indications that extinction is not just "unlearning" but constitutes a novel learning process distinct from original acquisition. Although extinction was first described more than 100 years ago by Russian physiologist Ivan Pavlov, many aspects of this phenomenon are still poorly understood. This is unfortunate, given that theories on the development and treatment of psychiatric disorders in part rely on extinction - e.g. psychotherapeutic interventions for phobias or psychological treatment of drug abuse.
In the next three years, the research units expected to make significant contributions to our understanding of the neural and behavioral mechanisms of extinction learning. The scope of the projects within the unit ranges from basic research in animal models and humans to clinical applications in the treatment of phobias, enabling efficient transfer of insight gained from basic research to outpatients seeking treatment for anxiety disorders.
Die ELH Studie zur emotionalen Bindung zu einem Roboter ist Thema im WDR Fernsehen bei Quarks & Co
On Thursday, Oct 24th delegates from alle German ultra-high field (UHF) sites met at the ELH institute for the GUFI kick-off meeting. GUFI means "German Ultra-high Field Imaging" and is a core facility funded by a grant from the German Research Foundation (DFG). It consists of a network of university and non-university research institutes in Berlin, Bonn, Essen, Freiburg, Heidelberg, Jülich, Leipzig, and Tübingen which operate human MRI imagers with 7 or 9.4 Tesla magnetic field strength. The grant duration is three years.
The goal of the GUFI network is to make the very expensive and highly complex UHF MR technology accessible to a larger number of researchers through organizational cooperation. On the technical level, the project involves the exchange of latest imaging protocols and in particular the development of new approaches to ensure common quality standards for image and spectral data, optimized for the challenges of UHF MR systems. These standards will assure that measurements can be conducted under ideal conditions and that measurements on different UHF MR systems can be compared.
Am Mittwoch, 23. Oktober besuchte Prof. Kurt Wüthrich das ELH, um sich im Rahmen eines Mentorenprogramms der Universität Duisburg-Essen mit Doktoranden und jungen Postdocs über ihre Forschung auszutauschen. Prof. Wüthrich erlangte Berühmtheit für seine bahnbrechenden Arbeiten zur Strukturaufklärung von Proteinen mittels kernmagnetischer Resonanzspektroskopie. Zusammen mit John B. Fenn und Koichi Tanaka wurde ihm im Jahr 2002 der Nobelpreis für Chemie verliehen. Neben seinem Vortrag mit dem Titel "1963 to 2013 – A Personal View of 50 Years with EPR, NMR and MRI" fand ein gemeinsames Mittagessen und eine Posterpräsentation mit den Doktoranden statt.
Prof. Dr. Mark E. Ladd was honored during the Erwin L. Hahn lecture for his outstanding service and contribution as founding director of the institute from 2005 till 2013.
Together with our friends from University Medical Center Utrecht we will again organize an ESMRMB lecture on RF simulation for MR systems: coil design and safety. This time, the course will be held in Utrecht, December 12-14. For more information please visit the ESMRMB website.
Eigentlich ist es nur eine Maschine, sagt uns der Verstand. Aber davon lässt sich das Gefühl anscheinend nicht beeindrucken. Wenn Roboter misshandelt werden, leiden die Zuschauer mit. Zu diesem Ergebnis kommen Forscher der Lehrstühle "Sozialpsychologie: Kommunikation und Medien", "Allgemeine Psychologie: Kognition" sowie des "Erwin L. Hahn Instituts für Magnetresonanztomographie". Mehr dazu hier:
Alumni-Newsletter (Seite 5)
Campus Report (Seite 10)
Kürzlich wurden 2 neue Publikationen aus dem ELH bei der renommierten Zeitschrift Investigative Radiology (impact 5.46) angenommen. In seiner technischen Arbeit "Comparison of Fat Saturation Techniques for Single-Shot Fast Spin Echo Sequences for 7T Body Imaging" untersucht Sören Johst verschieden Fettsättigungstechniken in der abdominellen Bildgebung bei 7 Tesla. In der klinischen Studie "Ultra-high-field Imaging of the Biliary Tract at 7 Tesla: Initial Results of Gd-EOB-DTPA-enhanced Magnetic Resonance Cholangiography (MRC) Investigative Radiology" untersucht Anja Fischer den erstmaligen Einsatz von Gadoxetsäure bei 7T in vivo, einem hochspezifisches Kontrastmittel für die Detektion und Charakterisierung von Leberläsionen. Beide Arbeiten werden in Kürze online verfügbar sein.
This year’s Erwin L. Hahn Lecture will be held in conjunction with a workshop examining the latest developments in fMRI. This will provide a complementary programme to the 7th Erwin L. Hahn Lecture, which will be given by Professor Kamil Ugurbil of the Center for Magnetic Resonance Research at the University of Minnesota. Prof. Ugurbil is renowned as one of the pioneers of high field human imaging, and his laboratory played a leading role in the discovery of fMRI. In more recent years he has played a leading role in the Human Connectome Project. Amongst other awards and recognitions he is a recipient of the Gold Medal of the International Society for Magnetic Resonance in Medicine.
Das ELH-Team gratuliert von ganzem Herzen Herrn Dr. Stephan Orzada zur erfolgreichen Verteidigung seiner Dissertation "New Excitation Concepts for Ultra-High-Field Human MRI". Die öffentliche Verteidigung fand am 28. Mai an der Radboud Universität Nijmegen statt.
Ob 7, 9.4, 10.5 oder 11.7 Tesla – technisch sind diese Feldstärken mittlerweile möglich – aber sind sie auch nötig? Lesen Sie mehr dazu in einem kürzlich erschienenen Artikel bei European Hospital:
Probleme und Chancen der Hochfeld-MRT
von Mark E. Ladd und Michael Bock
Seit Einführung der Magnetresonanztomographie (MRT) in die Klinik Anfang der 1980er Jahre hat die MRT kontinuierlich an Bedeutung gewonnen. In einer Umfrage wurden Internisten gebeten, die 30 wichtigsten Entwicklungen in der Medizin in den letzten 25 Jahren einzuordnen – Nummer 1 in dieser Liste waren die Schnittbildverfahren MRT und CT! Die Bedeutung der MRT in der modernen Diagnostik und Forschung wird auch durch die weltweit steigende Zahl an Tomographen belegt; inzwischen sind ca. 30.000 MRT-Systeme installiert, an denen jedes Jahr über 70 Mio. Untersuchungen durchgeführt werden.
Wenn Sie mehr drüber lesen möchten, können Sie sich hier den ganzen Artikel als pdf herunterladen.
In the run-up of the 63rd Annual International Communication Association conference in London in June, ELH scientists Astrid Rosenthal-von der Pütten, Nicole Krämer, and Matthias Brand are currently receiving high interest from many scientific communication networks such as SCIENCE or PHYS.ORG for their study on brain correlations of human-robot interaction in contrast to human-human interactions. For further information, please observe the following reports:
The journal Medical Physics has recently accepted our publication on "MR Safety Assessment of Potential RF Heating from Cranial Fixation Plates at 7 Tesla" (Oliver Kraff, Karsten H. Wrede, Tobias Schoemberg, Philipp Dammann, Yacine Noureddine, Stephan Orzada, Mark E. Ladd, and Andreas K. Bitz). The full publication will soon be available online at http://online.medphys.org/
On Saturday, March 2nd a hands-on on the topic "Uniform Body Imaging at 7T" within the framework of the ISMRM Ultra-High Field Workshops in Noordwijk was hosted at the ELH. International guests from Minnesota, Stanford, Brisbane, Marseille and Utrecht came to the ELH, to learn about theoretical and practical basics of the in-house developed technique TIAMO, with which a uniform excitation of the human torso is possible.
The work that was cited the most externally during the past 5 years from the journal "RöFo" is the one of Christoph Mönninghoff about 7T and aneurysms.
Evaluation of intracranial aneurysms with 7 T versus 1.5 T time-of-flight MR angiography - initial experience. Mönninghoff C, Maderwald S, Theysohn JM, Kraff O, Ladd SC, Ladd ME, Forsting M, Quick HH, Wanke I. Rofo. 2009 Jan;181(1):16-23. doi: 10.1055/s-2008-1027863. Epub 2008 Dec 29.
Hier sind die Termine im ersten Halbjahr 2013 für das MR Sicherheitstraining:
Mittwoch 23.01. 10:30 ELH Konferenzraum
Mittwoch 06.02. 15:00 UK Essen Bildungsakademie
Montag 18.02. 17:00 ELH Konferenzraum
Mittwoch 13.03. 15:00 UK Essen Bildungsakademie
Mittwoch 17.04. 15:00 UK Essen Strahlenklinik
Am 06.02. und 13.03. findet das Training im Seminarraum 4/5 im Hohlweg 18 an der Bildungsakademie der Uniklinik Essen statt. Am 17.04. findet das Training im Besprechungsraum der Röntgendiagnostik in der Strahlenklinik der Uniklinik Essen statt.
Mehr als 60 niederländische Magnetresonanzforscher fanden sich jetzt in der Universitätsstadt Essen zu ihrem Jahrestreffen ein. "Für uns ist das ganz normal, manchmal gehört Essen eben zu den Niederlanden", betont der Amerikaner Prof. Mark Ladd, der seit 13 Jahren in der Ruhrgebietsmetropole forscht und das Erwin L. Hahn Institut (ELH) als einer der Direktoren leitet. Das ELH ist eine gemeinsame Einrichtung der Universität Duisburg-Essen (UDE) und der Radboud Universiteit Nijmegen (RUN).
Häufig sind die Nijmegener Forscher in Essen, wöchentlich finden Videokonferenzen zwischen den beiden Standorten statt. Derzeit ist der Engländer Prof. David Norris, der seit zehn Jahren an der RUN forscht, geschäftsführender Direktor des ELH. Was liegt da näher, als die jährliche Erwin L. Hahn Lecture mit dem Treffen der niederländischen 7 T-MRT-Forscher zu kombinieren? Das die Idee gut war, zeigt die Tatsache, dass die Hälfte der über 120 Tagungsteilnehmer aus den Niederlanden angereist ist. Nur einer passte nicht recht ins deutsch-niederländische Bild: der Sprecher der Erwin L. Hahn Lecture, Prof. Daniel Sodickson. Er forscht an der New York University.
The Erwin L Hahn Institute is honored to announce the appointment of Mark E Ladd, Ph.D., as deputy editor of the prestigious journal Magnetic Resonance in Medicine.
Dr. Oliver Kraff has recently been awarded with the Erwin L Hahn Institute award for young scientists for his Ph.D. thesis "Loop Radiofrequency Coils for Clinical Magnetic Resonance Imaging at 7 Tesla" published in 2011.
This October we will hold the 6th Erwin L. Hahn Lecture in conjunction with the annual VISTA (Virtual Institute for Seven Tesla Applications) workshop in Essen. We are pleased to announce that this year's distinguished lecturer will be Professor Dan Sodickson of New York University.
Participation is free.
Deadline for registration is October 1st, 2012.
We look forward to welcome you in Essen.
The latest edition of EMRF's successful textbook "Magnetic Resonance in Medicine" is now available as an e-learning site on the web. It is accessible free of charge. Take a look at www.magnetic-resonance.org
This year the ELH opens again for the Extraschicht on Saturday, June 30th. Visitors are welcome to join talks and discussions with the scientists about the institute, research and MRI at 7T. Come over - We are there for you from 6pm until midnight!
Der Kongress der European Society of Gastrointestinal and Abdominal Radiology, dieses Jahr vom 12.06.-15.06.2012 in Edinburgh, zeichnet jährlich die 20 besten Abstracts aller eingereichten Beiträge aus. Dieses Jahr wurde folgender wissenschaftlicher Abstract von Anja Fischer als TOP 20 ausgezeichnet und am 15.06. als Vortrag auf dem Kongress präsentiert: Ultra-High-Field imaging of the biliary tract at 7 Tesla: initial results of Gd-EOB-DTPA-enhanced MRCP (Fischer A, Kraff O, Orzada S, Schäfer LC, Ladd ME, Umutlu L, Lauenstein TC). Der Beitrag handelt von der erstmaligen Darstellung der Gallenwege mittels Ultrahochfeld MRT bei 7 Tesla. Die Gallengänge wurden mit Hilfe des leberspezifischen Kontrastmittels Gadoxetsäure in T1-gewichteten Sequenzen in hoher Auflösung dargestellt. Die T2-gewichtete Bildgebung zeigte im Vergleich zur klinisch etablierten MRCP bei 3 Tesla noch eine deutlich eingeschränkte Bildqualität auf Grund von B1-Artefakten und SAR Limitation. Die Untersuchung von Patienten mit Gallenwegsveränderungen nach Lebertransplantation ist Fokus zukünftiger Studien.
Cooperating scientists from the Erwin L. Hahn Institute for MRI and the Department of Psychiatry & Psychotherapy, LVR-Clinics Essen including David Norris from the Donders institute recently received full funding from the review for the Helmholtz Alliance ICEMED. The project will look at 'changes in glutamate and GABA measured with proton magnetic resonance spectroscopy at 7T in the brains of patients with type II diabetes treated with nasally administered insulin'.
"We can start tomorrow", said Prof. Mlynek (president of the Helmholtz Alliance) due to the fact that the review responded extremely positive about the proposal and stated full funding of 30M €. Hereof 50% has to be carried by the partners themselves as outlined in the application.
The scientists will soon investigate the modulations in the concentrations of the important metabolites glutamate and GABA resulting from the regular application of the nasal spray. This will be measured and correlated with changes in: neuropsychological performance; activation studies; and changes in resting state connectivity of the brain. The study will yield important insights into the mechanisms by which the insulin spray improves cognitive performance and the efficacy over a range of behavioural domains: this will lead in turn to an improvement in therapeutic treatment for T2D patients.
Herausragende Wissenschaftler mit einem exzellenten Forschungsvorhaben haben eine zwölfprozentige Chance, mit dem begehrten Advanced Investigators Grant des European Research Councils (ERC) ausgezeichnet zu werden. Genau dies hat jetzt Prof. Dr. Mark Ladd geschafft: Der Experte für Magnetresonanztomographie (MRT) an der Universität Duisburg-Essen (UDE) hat den ehrenvollen Ritterschlag der europäischen Forscherwelt erhalten, verbunden mit 2,1 Mio. Euro, um das vorgeschlagene Projekt umsetzen zu können.
Prof. Ladd (44) ist grenzüberschreitendes Arbeiten gewohnt. Als er vor acht Jahren auf die Professur für Biomedizinische Bildgebung am Institut für Diagnostische und Interventionelle Radiologie am Universitätsklinikum Essen berufen wurde, hatte er zuvor an der Stanford Universität seinen Master in Electrical Engineering erworben und an der renommierten ETH Zürich promoviert. Seit fünf Jahren ist Ladd zusätzlich Direktor des Erwin L. Hahn Instituts (ELH), einer gemeinsamen Einrichtung der Universität Duisburg-Essen und der Radboud-Universität in Nimwegen.
Das ELH-Team auf dem Gelände der ehemaligen Kokerei Zollverein hat die bundesweit seltene Chance, an einem 7 Tesla-Magnetresonanztomographen (MRT) forschen zu können. Das außergewöhnlich starke Magnetfeld dieses Gerätes ermöglicht viel genauere Einblicke ins Körperinnere als bisher übliche Diagnoseverfahren. Allerdings ist hierfür auch eine völlig neue Technologie notwendig. Dass sie diese beherrschen, haben die ELH-Forscher schon des Öfteren zeigen können. So waren sie beispielsweise 2010 weltweit die Ersten, die ein 7 Tesla-MRT-Bild vom gesamten Körper aufgenommen haben.
Mark Ladd: "Wir wollen die beeindruckenden Möglichkeiten dieser neuen Technologie für die Patienten-Diagnose erschließen. Mit den neu eingeworbenen EU-Geldern sollen neue Konzepte für die Aufnahme der Bilddaten und die Sicherheit der Patienten entwickelt werden. Ärzten werden so schon in wenigen Jahren in der Lage sein, Krankheiten früher bzw. genauer zu erkennen."
Within the next weeks three new students from the universities of Bochum and Gelsenkirchen will start their Bachelor theses regarding coil engineering, sequence development and image analysis. Welcome to the team: Maike Lindemann, Anna Voss and Katarzyna Kujawa.
Two abstracts from the ELH for the upcomming conference of the International Society for Magnetic Resonance in Medicine (ISMRM) have been awarded. Stephan Orzada has been awarded the Magna Cum Laude Merit Award for his abstract entitled "A 16-channel micro strip Tx/Rx array for bilateral breast imaging at 7 Tesla". Dr. Oliver Kraff has been awarded the Summa Cum Laude Merit Award for his abstract entitled "7 Tesla MRI of the shoulder and upper extremities using an 8-channel Tx/Rx Coil". These awards were given to PhD students and young Post-Docs whose abstract scored in the top 15% (magna cum laude) or 3% (summa cum laude), respectively, of all abstracts submitted to the same general category. Congratulations!
The rectorate of the University Duisburg-Essen hat granted Dr. Oliver Kraff research funds within the internal program for young academics. The funds will help Dr. Kraff to continue his work in radiofrequency coil engineering and to acquire further grants for future research projects.
On December 6-8, 2012 the Erwin L. Hahn Institute and the University of Duisburg-Essen will host a course on RF simulation for MR Systems. The course is part of the workshop series "Lectures on MR" of the European Society for Magnetic Resonance in Medicine and Biology (ESMRMB).
For more information and registration, please visit http://www.esmrmb.org/.
A study from Sören Johst with the title "Time-of-Flight MR Angiography at 7 T using Venous Saturation Pulses with Reduced Flip Angles" has been accepted for publication by Investigative Radiology (impact 4.67). This work shows an improved suppression of the venous system in TOF MRA protocols with reduced SAR at 7 Tesla, enabling acquisition of high resolution angiograms in acceptable imaging time.
The ELH institute is part of the Euro-BioImaging infrastructure, which conducts a series of proof-of-concept sudies and offers free access to European advanced biological and biomedical imaging facilities and cutting-edge imaging technologies. Detailed information on the proof-of-concept studies and proposal submission are provided at www.eurobioimaging.eu
The ELH team congratulates Dr. Peter Jan Koopmans to the successful defence of his dissertation "fMRI of cortical layers". The public defence was held at the Radboud University in Nijmegen on September 19th. In his dissertation, Dr. Koopmans has developed techniques to increase the spatial resolution of fMRI to such a level that cortical depth dependent signal changes can be distinguished. This allows new possibilities for cognitive neuroimaging.
The German Chapter of the ISMRM has awarded Stephan Orzada from our team with the third prize of the Gorter Award 2011 at the 14th annual meeting in Berlin. With the Gorter Award, the German Chapter honours the three best abstracts from young scientists in medicine and natural sciences working in the field of magnetic resonance imaging. Stephan Orzada has been honoured for his work "Time Interleaved Acquisition of Modes (TIAMO)" which allows abdominal imaging at 7 Tesla without signal dropouts.
The Erwin L Hahn Institute will celebrate its 5th anniversary this coming October. To mark the occasion there will be a one-day symposium which will examine the current state of MR at 7T. The overriding question of the day will be: What justifies the investment in ultra-high-field MR?
We have invited five internationally acknowledged experts in the field to give state-of-the-art talks about specific 7T advancements and potential constraints. The talks will highlight technical and fundamental research aspects as well as several applications of ultra-high-field MR in radiology and cognitive neuroscience. Following the talks, experts in the field of 7T MR will discuss the future benefits and risks related to investing in ultra-high-field MR.
We hereby cordialy invite you to join us on the occasion of the 5th Erwin L. Hahn Lecture, which will take place on October 12, and look forward to welcoming you to this exciting event.
On December 8 - 10, 2011 the ELH will host a course of the European Society for Magnetic Resonance in Medicine and Biology (ESMRMB). The course is part of the workshop series '2011 Lectures on Magnetic Resonance'.
For more information and registration, please visit www.esmrmb.org.